![]() Rugo presented the main results of the SWISH trial, with outcomes spanning the duration of the study. 2Īt the 2016 Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology International Symposium on Supportive Care in Cancer in Adelaide, Australia, Dr. 1 The comparator was historical data from the BOLERO-2 trial. ![]() The SWISH trial sought to evaluate an alcohol-free, steroid mouthwash to prevent grade ≥ 2 stomatitis in patients with HER2-positive advanced breast cancer receiving everolimus/exemestane. Rugo said at the 2016 Palliative Care in Oncology Symposium. “This should be considered a new standard of oral care in this setting,” Dr. Rugo, MD, principal investigator of the SWISH trial and Director of Breast Oncology and Clinical Trials Education at the University of California Helen Diller Family Comprehensive Cancer Center, San Francisco. ![]() Throw away any unused Dexamethasone Intensol™ solution 90 days after the bottle is opened for the first time.Dexamethasone mouth rinse should be given prophylactically to prevent stomatitis associated with everolimus (Afinitor)/exemestane in metastatic breast cancer, according to Hope S. Keep from freezing.ĭo not keep outdated medicine or medicine no longer needed.Īsk your healthcare professional how you should dispose of any medicine you do not use. ![]() Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. If you miss a dose of this medicine, take it as soon as possible. Your doctor may adjust your dose as needed.Īdults-20 or 40 milligrams (mg) once a day.Ĭhildren-Use and dose must be determined by your doctor. At first, 0.02 to 0.3 mg per kilogram (kg) of body weight per day, divided and taken 3 or 4 times a day. Your doctor may adjust your dose as needed.Ĭhildren-Dose is based on body weight and must be determined by your doctor. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.įor oral dosage forms (solution, tablets):Īdults-At first, 0.75 to 9 milligrams (mg) per day. The amount of medicine that you take depends on the strength of the medicine. If your dose is different, do not change it unless your doctor tells you to do so. The following information includes only the average doses of this medicine. Follow your doctor's orders or the directions on the label. The dose of this medicine will be different for different patients. ![]() You may need to slowly decrease your dose before stopping it completely. If you use this medicine for a long time, do not suddenly stop using it without checking first with your doctor. You may take Hemady™ with or without food. Stir the mixture well and drink or eat it right away. The liquid should be added to water, juice, soda or a soda-like beverage, applesauce, or pudding. Measure the concentrated liquid with the special oral dropper that comes with the package. The Dexamethasone Intensol™ solution is a concentrated liquid. The average household teaspoon may not hold the right amount of liquid. Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. ![]()
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